PLOS Biology

Targeting of conserved spike epitopes enables broad antibody neutralisation of diverse bat sarbecoviruses

Researchers have identified and structurally characterized three cross-reactive monoclonal antibodies that neutralize diverse sarbecoviruses and SARS-CoV-2 variants. The study focuses on antibodies V1WT_06, V1WT_41, and VA14_26, which target conserved receptor-binding domain epitopes on the viral…